diff --git a/cmd/uncloud/service/run.go b/cmd/uncloud/service/run.go
index 89d404e2..82515456 100644
--- a/cmd/uncloud/service/run.go
+++ b/cmd/uncloud/service/run.go
@@ -13,14 +13,16 @@ import (
 )
 
 type runOptions struct {
-	command  []string
-	image    string
-	machines []string
-	mode     string
-	name     string
-	publish  []string
-	replicas uint
-	volumes  []string
+	command           []string
+	entrypoint        string
+	entrypointChanged bool
+	image             string
+	machines          []string
+	mode              string
+	name              string
+	publish           []string
+	replicas          uint
+	volumes           []string
 
 	cluster string
 }
@@ -35,6 +37,7 @@ func NewRunCommand() *cobra.Command {
 		RunE: func(cmd *cobra.Command, args []string) error {
 			uncli := cmd.Context().Value("cli").(*cli.CLI)
 
+			opts.entrypointChanged = cmd.Flag("entrypoint").Changed
 			opts.image = args[0]
 			if len(args) > 1 {
 				opts.command = args[1:]
@@ -44,6 +47,8 @@ func NewRunCommand() *cobra.Command {
 		},
 	}
 
+	cmd.Flags().StringVar(&opts.entrypoint, "entrypoint", "",
+		"Overwrite the default ENTRYPOINT of the image. Pass an empty string \"\" to reset it.")
 	cmd.Flags().StringVar(&opts.mode, "mode", api.ServiceModeReplicated,
 		fmt.Sprintf("Replication mode of the service: either %q (a specified number of containers across "+
 			"the machines) or %q (one container on every machine).",
@@ -128,6 +133,14 @@ func run(ctx context.Context, uncli *cli.CLI, opts runOptions) error {
 		Ports:    ports,
 		Replicas: opts.replicas,
 	}
+
+	// Overwrite the default ENTRYPOINT of the image or reset it if an empty string is passed.
+	if opts.entrypoint != "" {
+		spec.Container.Entrypoint = []string{opts.entrypoint}
+	} else if opts.entrypointChanged {
+		spec.Container.Entrypoint = []string{""}
+	}
+
 	if err := spec.Validate(); err != nil {
 		return fmt.Errorf("invalid service configuration: %w", err)
 	}
diff --git a/internal/api/container.go b/internal/api/container.go
index 4e771c07..f99e4589 100644
--- a/internal/api/container.go
+++ b/internal/api/container.go
@@ -75,10 +75,11 @@ func (c *Container) ServiceSpec() (ServiceSpec, error) {
 	//  is created. Figure out how to get a spec that is equal to the initial spec.
 	return ServiceSpec{
 		Container: ContainerSpec{
-			Command: c.Config.Cmd,
-			Image:   c.Config.Image,
-			Init:    c.HostConfig.Init,
-			Volumes: c.HostConfig.Binds,
+			Command:    c.Config.Cmd,
+			Entrypoint: c.Config.Entrypoint,
+			Image:      c.Config.Image,
+			Init:       c.HostConfig.Init,
+			Volumes:    c.HostConfig.Binds,
 		},
 		Mode:  c.ServiceMode(),
 		Name:  c.ServiceName(),
diff --git a/internal/api/service.go b/internal/api/service.go
index 9c2480dc..669bba8b 100644
--- a/internal/api/service.go
+++ b/internal/api/service.go
@@ -67,8 +67,11 @@ func ValidateServiceID(id string) bool {
 }
 
 type ContainerSpec struct {
+	// Command overrides the default CMD of the image to be executed when running a container.
 	Command []string
-	Image   string
+	// Entrypoint overrides the default ENTRYPOINT of the image.
+	Entrypoint []string
+	Image      string
 	// Run a custom init inside the container. If nil, use the daemon's configured settings.
 	Init *bool
 	// List of volumes to bind mount into the container.
diff --git a/internal/cli/client/container.go b/internal/cli/client/container.go
index 8ff7c125..c050a2be 100644
--- a/internal/cli/client/container.go
+++ b/internal/cli/client/container.go
@@ -42,9 +42,10 @@ func (cli *Client) CreateContainer(
 
 	// TODO: calculate the spec hash and set it as a label to detect changes in the service spec.
 	config := &container.Config{
-		Cmd:      spec.Container.Command,
-		Hostname: containerName,
-		Image:    spec.Container.Image,
+		Cmd:        spec.Container.Command,
+		Entrypoint: spec.Container.Entrypoint,
+		Hostname:   containerName,
+		Image:      spec.Container.Image,
 		Labels: map[string]string{
 			api.LabelServiceID:   serviceID,
 			api.LabelServiceName: spec.Name,